Lugar: San Juan y San Vicente (Jorge Juan, 18)

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9:00–12:55 SESSION 3 Modified Nucleosides, Nucleotides and Nucleic Acids (chair Miguel Ferrero)

9:00-9:45 Harnessing the Power and Potential of Palladium Catalysis for the Synthesis of Chemically Modified Nucleosides. Yogesh S. Sanghvi (invited speaker)

9:45-10:05 Engineering DNA-based nanostructures for bioimaging and biomimetics. Silvia Hernández-Ainsa

10:05-10:25 Bioconjugation reactions involving 1,2,4,5-tetrazines. Jordi Agramunt

10:25-10:45 Non-coding RNAs carried by gold or magnetic nanoparticles for the treatment of rare diseases. Paula Milán

10:45-11:05 Photoinduced oxidation and reduction ring splitting of bipyrimidine-derived azetidines: a multifaceted approach. Virginie Lhiaubet-Vallet

11:05-11:35 COFFEE BREAK

11:35-11:55 Pro-cNMPs as novel chemical tools for cell-based assays. Chris Meier

11:55-12:15 A nanoparticle-based ligand for CuAAC fluorogenic "click" reactions in water. Ciro Rodríguez Díaz

12:15-12:35 Correction of point mutations of the aprt gene in mammalian cells by Repair-PolyPurine Reverse Hoogsteen hairpins. Álex J. Félix

12:35-12:55 Fluorescent derivatives for the detection and stabilization of i-motifs. Bartomeu Mir

13:00-14:30 LUNCH

14:30-16:15 SESSION 4 Advances in Nucleic Acids structure and function (chair Carlos González)

14:30-15:15 Advances in structural mass spectrometry to study nucleic acids folding and ligand interactions. Valérie Gabelica (invited speaker)

15:15-15:35 Atomistic insight into sequence-directed DNA bending and minicircle formation propensity in the absence and presence of phased A-tracts. Alberto Mills

15:35-15:55 Functional mechanism of the 3'X RNA domain of hepatitis C virus. José Gallego

15:55-16:15 Solution equilibria of a guanine-rich sequence near the promoter region of the SMARCA4 gene. Raimundo Gargallo

16:15-16:20 Closing speech